The warped misadventures of a former boy genius turned washed-up, middle-aged mad scientist Dr. Rusty Venture; his moronic teenage sons; their maniac bodyguard; and the Doctor's arch-nemeses, incompetent super villain Th…

话说在纽约市的下水道之中住着四只功夫高强的忍者龟，它们跟随着忍者师父—一只来自日本的超级大老鼠。一次偶然机会，它们救了一名正义的电视女记者，她也成为了唯一知道忍者龟藏身处的人。在多次行侠仗义后，他们与城市里的一个神秘组织…